abstract:UGGT, or (UDP)-glucose:glycoprotein glucosyltransferase (160kDa) is a soluble enzyme resident in the lumen of the endoplasmic reticulum (ER). The main function of UGGT is to recognize misfolded glycoproteins and transfer a glucose (Glc) monomer (monoglucosylate) to the terminal mannose on the glycoprotein.