Known as the Tykerb Evaluation After Chemotherapy (TEACH), this study is also sponsored by the manufacturer. Dr.

这项被称为TEACH (Tykerb化疗后评估)的研究也是由生产商赞助的。

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Tykerb works by depriving tumor cells of signals needed to grow. Tykerb enters the cell and blocks the function of the HER2 protein.

拉帕替尼能阻断肿瘤细胞生长的信号，进入细胞后能阻止HER2蛋白发挥作用。

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The FDA approval of Tykerb was based on the results of a study involving approximately 400 breast cancer patients with advanced-stage HER2 disease.

FDA参照大约400例晚期her 2阳性的乳腺癌病例的研究结果的基础上，批准了拉帕替尼应用于临床。

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It has rejected some expensive cancer drugs, including Avastin for colon cancer and Tykerb from GlaxoSmitkline for breast cancer.

FORBES: Drawing The Line On Overpriced Cancer Drugs

In the EMILIA study, people receiving Kadcyla survived a median of 5.8 months longer compared to those taking Tykerb and Xeloda.

FORBES: A Triumph In Breast Cancer -- And Another Expensive Drug

At the two-year mark, 65.4% of T-DM1 patients were alive, compared to 47.5% of patients receiving Xeloda and Tykerb, researchers said.

WSJ: Roche Breast-Cancer Treatment Advances