The researchers believe that the flawed version of FTO is more active than the normal one and 'turning it down' could dampen appetite.

研究人员认为，有缺陷的FTO比正常基因更活跃，“把它关掉”就有可能抑制食欲。

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In at least one bacterium, Dr Blackwell and her fellow researchers are working on a way to turn up the volume instead of turning it down.

在不止一种细菌上，Blackwell博士的团队发现了升高而不是降低AHL量的方法。

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Benitez was handed a four-year contract in midweek however, he stunned Tom Hicks and George Gillett by turning it down for the fifth time.

周中，贝尼特斯收到了一份为期四年的合同，然而，他拒绝了第五次合同令汤姆·希克斯和吉列震惊。

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And what is the balance of risk between accepting the current deal and turning it down?

ECONOMIST: Ever closer

Deputy leader of Gravesham council, Lee Croxton, said there had been "no good planning reasons" for turning it down.

BBC: Artist's impression of development

In at least one bacterium, Dr Blackwell and her fellow researchers are working on a way to turn up the volume instead of turning it down.

ECONOMIST: Novel antibiotics