The office was turned upside-down.

办公室被弄的乱七八糟。

youdao

When his wife died, his entire world was turned upside down.

他妻子死后，他的整个生活变得一塌糊涂。

《牛津词典》

Her life was turned upside down when a motorist distracted by his cell phone, ran a stop sign and crashed into the side of her car.

一名驾车者被手机分了心，闯了一个红灯，撞到了她的车边。从此，她的生活被颠覆了。

youdao

His nineteen-oh-seven painting "Les Demoiselles d'Avignon" turned the art world upside down.

VOA: special.2010.03.24

It wouldn't be the same if I turned it upside down because the carbons - the rings here, the pentose's would all be turned over, the chemistry would look different and the sequence of bases would look different.

记住单链倒过来,就和原来不一样了,这是因为碳原子和糖环结构,戊糖会翻转,使得这个化学结构看起来不一样了,碱基的顺序也不一样了

耶鲁公开课 - 生物医学工程探索课程节选

Stewart returns as Bella and says the year since the original Twilight film has turned her character's life upside-down.

VOA: standard.2009.11.23

It was a decade in which it seemed like the values that built this country were turned upside-down.

WHITEHOUSE: American Jobs Making Advanced Batteries

We stepped into Asia Crafts next door, where silver-tongued Kashmiris unrolled carpets that seemed to change colour every time they were turned upside-down.

BBC: The man in the white tunic

Disappointment and then the September 2001 attacks on New York and Washington, took America's attention, as the world turned upside-down once more.

ECONOMIST: Welcome to the new world disorder