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Conclusion CD147 and VEGF are over-expressed in TSCC and can be used as a reliable indicator for the biological behaviors of TSCC and its clinical therapy.
结论CD 147和VEGF在舌鳞癌组织中呈过表达,两者的联合检测可以做为判断舌癌生物学行为和指导临床治疗的指标。
Objective: to study the expressions of PTEN and extracellular signal-regulated kinase (ERK) and their clinical significance in tongue squamous cell carcinoma (TSCC).
目的:研究pten、细胞外信号调节激酶(ERK)表达及与舌鳞状细胞癌(TSCC)临床病理参数的关系。
Methods:Immunohistochemistry and PCR-SSCP were used to detect the expression of P53 protein and p53 gene mutation in 32 cases of TSCC and 10 cases of tongue leukoplakia.
方法:应用免疫组织化学和聚合酶链反应—单链构象多态性分析(PCR-SSCP)检测10例舌白斑和32例舌癌,并结合临床资料进行分析。
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