Carrying out this sort of cyber snooping does not take an encyclopaedic knowledge of computers or hours of trial and error.

BBC: Snooping goes hi-tech

When researching antibiotics, candidate substances are identified either by computer modeling or good old-fashioned trial and error in the lab.

FORBES: Is Your Doctor Relying On Bad Information?

To create breakthrough innovation in cooking is not by the classic scientific method of carefully-planned-in-advance-and-in-detail research, or teleological, activities, but through trial and error.

FORBES: For Innovation, Knowledge is a Poor Substitute for Experimentation