At the peak of arthritis, the rats showed tri-legged gait, and severeedema in the tissue, as well as hydrarthrosis with massive leukocytes infiltrating into jointcavityand the tissuearound.
In 2009, the RIKEN-TRI Collaboration Center for Human-Interactive Robot Research (RTC), a joint project established in 2007 and located at the Nagoya Science Park in central Japan, unveiled a robot called RIBA (Robot for Interactive Body Assistance) designed to assist in this task.