abstract:The transmission disequilibrium test (TDT) was proposed by Spielman, McGinnis and Ewens (1993) as a family-based association test for the presence of genetic linkage between a genetic marker and a trait. It is an application of McNemar's test.
The haplotype-based haplotype relative risk( HHRR ) andtransmissiondisequilibriumtest ( TDT ) methodswere used to analyze the association betweenDRD4and ADHD.