DNA strand scission and topology changes are catalyzed by DNA topoisomerases.
DNA拓扑异构酶与断开dna链和改变其拓扑结构有关。
The specific inhibitors of DNA topoisomerases are the useful tool in studying their biological functions.
寻找及发现其抑制剂是研究它的生物学功能的重要途径。
Another example is that of researchers at GlaxoSmithKline who recently described a novel class of antibacterial agents that target type IIA topoisomerases.
另一个例证是，葛兰素史克公司的研究人员最近描述了一种以iia型拓扑异构酶为作用目标的新的抗菌剂。
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