To defile means to make dirty or impure.

玷污就是弄脏，使一个人变得不纯洁。

youdao

For: it is impossible to copy the classic, therefore it is unnecessary to defile it.

正方：经典是无法复制的，所以没必要去亵渎经典。

youdao

These are the things which defile a man: but to eat with unwashen hands defileth not a man.

这都是污秽人的。 至于不洗手吃饭，那却不污秽人。

youdao

In very severe cases, it can even defile some common objects, and in those cases, the source of impurity might have to be isolated or excluded if necessary.

在一些非常严峻的情况中，它会玷污一些普通的事物，在这种时候，不洁之源,也许只能被孤立，严重的话需要驱逐。

耶鲁公开课 - 旧约导论课程节选

We head uphill, across crumbly volcanic rock through a narrowing defile that rises to the top of a ridge.

BBC: Iceland on horseback