I am tired and lonely and I want to go home.

我疲惫而孤独，只想回家。

youdao

Having been busy for the same thing, I feel tired and lonely.

一直忙于一件事情容易感到厌烦和孤独。

youdao

Don't say "duh" yet until you've tried this for at least 24 hours, and, if you want an extra challenge, when you are hungry, angry, lonely or tired.

除非因为饥饿、愤怒、孤独或厌倦而忍无可忍必须要和他吵架，在万不得已的时尽量不要说伤害对方的话。

youdao

Father looked tired and lonely.

VOA: special.2009.03.07

Her offer of a magazine to a tired, scared and lonely soldier has echoed throughout my life.

NPR: The Connection Between Strangers