To create their therapy, the researchers drew a sample of each patient's blood in order to extract and modify a type of immune-system cell, called a T-cell, so that it would recognise the molecules found on the outer surface of melanomas. They did this by infecting the T-cells with genetically modified viruses carrying genes that coded for receptors to melanoma molecules. The viruses in question were retroviruses, which work by adding their genes to those of their host's cell nucleus. Thus re-armed, the T-cells were allowed to breed before being put back into the patient from whom they had originally been taken.

基于1个网页-相关网页