（2）阈值病变(threshold ROP)：ROPIII期，处于I区或II区，新生血管连续占据5个时钟范围，或病变虽不连续，但累计达8个时钟范围，同时伴plus。
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There was a trend for supplemental oxygen to reduce the progression to threshold ROP, however this did not reach statistical significance (RR 0.84, 95% CI 0.70, 1.02).
补充氧气有减低恶化至阀值的早产视网膜病变之趋势，然而没有构成统计学上的差异(RR 0.84, 95% CI 0.70, 1.02)。
Methods The randomized cohort originally consisted of 291 preterm children with birth weights less than 1251 g who developed a defined threshold of ROP severity in one or both eyes.
方法 ：本研究是随机队列研究，共有291名出生体重小于1251克单眼或者双眼有明确临界的早产儿视网膜病变的婴儿进入研究。
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