One problem is that they're not always accurate and there's a couple of factors that could lead them away from accuracy.

其中一个问题就是它们并不总是准确的,有几个因素,能减低它们的准确性。

耶鲁公开课 - 心理学导论课程节选

And one problem is that "For depression" is that there's too little of a neurotransmitter known as serotonin.

抑郁症的问题就在于,缺乏一种叫做血清素的神经递质

耶鲁公开课 - 心理学导论课程节选

OK. You can see that thing is cutting down the problem in half each time, which is good, but there's one more thing I need to deal with.

这很棒，但是我们还需要处理另外一件事情,让我们仔细来看看,我在开始做之前一直在说，应该先试验试验。

麻省理工公开课 - 计算机科学及编程导论课程节选

But there's one problem: Incumbents who jump into disruptive new markets invariably find that the amateurs have aced the core competancies and now command the sales and distribution choke points.

FORBES: Digital rules: The High-Margin Danger Zone

There's one problem: They are unable to feature the leading voices of patient care -- the American Medical Association and American Hospital Association -- because those organizations support reform as good for patients.

CNN: Repeal health care law? Forget about it

There's just one problem: there is no bell tower for the fatal plunges.

BBC: For the birds: Hitchcock��s California