One famous example is the Tuskegee syphilis study, which began in the nineteen thirties.
VOA: special.2010.07.21
Moreover, poor blacks harbour a strong mistrust of government doctors, mistrust that is partly a consequence of the notorious Tuskegeesyphilisstudy that ran between the 1930s and 1972.
The American Tradition Institute (ATI) which filed the law suit against EPA and its administrator asserts that such practices are not only illegal, but run afoul of virtually every rule of ethical standard established since World War II and theTuskegeesyphilis experiments to protect human study subjects from rogue scientific research.