Gene Mapping of human diseases, especially the complex genetic diseases, has been the difficulty and hotspot in medical genetics and gene study.
人类疾病，特别是多基因遗传病相关基因的定位，是目前医学遗传学和基因研究中的难点和热点。
It is the key and difficulty to choose right method to characterize the high heterogeneity of fractured rock media on the basis of range and precision of study object.
如何根据研究对象的范围和精度要求合理地表征裂隙岩体介质的非均质性是裂隙岩体渗流数值模拟的关键点和难点。
As the classic adjacent exits and entrances, weaving areas are the keystone and difficulty of traffic study.
交织区作为典型的相邻出入口，是交通领域研究的重点和难点。
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