A recent review of the Selenium and Vitamin E Cancer Prevention Trial showed long-term, regular use of Vitamin E supplements increase the risk of prostate cancer in healthy men.

最近，一项针对硒和维生素E抗癌试验的报告显示，长期规律服用维生素E补充剂会增加健康男性患前列腺癌的风险。

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In December, an analysis published in the Journal of the American Medical Association regarding the Selenium and Vitamin E Cancer Prevention Trial trial found that neither of the supplements provided a benefit in prostate cancer prevention.

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The Selenium and Vitamin E Cancer Prevention Trial involving 35, 000 U.S. and Canadian men was halted in October when researchers determined that selenium was not protecting the men from prostate cancer and may have been causing diabetes in some of them.

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Some experts have suggested that it may be more effective to supplement the minerals such as zinc and selenium that the body uses to produce catalase, MSR A and B, and tyrosinase, rather than take them directly.

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