Conclusi on: the firing of ventral pallidal neurons is excited prominently from morphine in the morphine dependent rats. Ventral pallidum has an important role in drug reward.
结论:吗啡显著兴奋吗啡依赖大鼠腹侧苍白球神经元,腹侧苍白球在药物强化过程中起着重要作用。
OBJECTIVE:To elucidate the effect of ondansetron(OND), a 5-HT3 receptor antagonist, on the morphine-induced conditioned place preference(CPP) in mice and its possible mechanism.
目的:探讨5-HT3型受体特异性拮抗剂奥丹西隆对吗啡诱导的条件性位置偏爱(CPP)效应的影响及其可能机制。
Objective:Using the outer-cell recording to observe the morphine responses of nucleus accumbens and ventral subiculum, and explore the function of them in the process of drug-dependence.
目的:用胞外记录的方法分别观察伏隔核和海马腹侧下托对吗啡的反应性,探讨其在药物心理依赖形成过程中所处的地位。
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