Let's focus our attention on the main problem and not get bogged down in minor issues.

抓主要问题，不要被枝节问题牵掣住。

《新英汉大辞典》

The main problem lies elsewhere.

主要的问题出在别的地方。

youdao

The main problem is today's fragmented habitats.

主要的问题是如今支离破碎的栖息地。

youdao

Experts say the public's poor opinion of the national economy, including high unemployment, is the main problem facing Democrats this year.

VOA: special.2010.10.30

Yeah, this is the main problem.

是，这是主要的问题。

关于罗马尼亚 - SpeakingMax英语口语达人

More fundamentally, I want to get back to what I think of as the main theme of 6.00, which is taking a problem and finding some way to formulate the problem so that we can use computing to help us get an answer.

花一些时间来讲,更重要的是我想，回到我认为的6。00的重点,即处理问题并公式化问题,从而使我们能够靠电脑得出答案。

麻省理工公开课 - 计算机科学及编程导论课程节选

The main problem appears to be the water management systems at Pascua Lama, El Mercurio reported.

FORBES: Barrick Gold Fined $16M For Environmental Problems At $5B Pascua Lama Project In Chile

Obviously, the main problem here is that the company leaves hiring decisions completely to managers.

FORBES: What Will Happen To The "Little Janie Qs" of Wal-Mart?

The main problem with breast implants, he says, is that they make mammography more difficult.

FORBES: Inamed Wants Silicone Back In Breast Implants