The heart of the problem is supply and demand.

问题的核心是供给和需求。

《柯林斯英汉双解大词典》

The heart of the problem is the looming patent "cliff" (see chart).

问题的核心是迫在眉睫的专利到期“悬崖”(见图表)。

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That might sound like a farce but it goes to the heart of the problem.

这可能看起来是个闹剧但它直指问题的中心。

youdao

So, many people have relatives they know of that have had to have their heart imaged -- heart disease is a major problem in the United States, and there's a good chance that they had Cardiolite given to them to help in that imaging process.

它被用在心脏成像中,很多人都有一些亲戚他们-,必须要做心脏成像，心脏病已经是美国的一个主要问题,而很有可能他们就要用到Cardiolite来成像。

麻省理工公开课 - 化学原理课程节选

These dimensions are at the heart of the problem and their solution will ultimately be decisive.

WHITEHOUSE: 5/10/10: White House Press Briefing

At the heart of the problem is a lot of debt that really cannot be repaid.

FORBES: Greek People Stuck With Stinking Debt

And that gets to the heart of the problem with Netanyahu's conditional support for Palestinian statehood.

CENTERFORSECURITYPOLICY: Netanyahu's perilous statecraft