The chairwoman is up against the greatest challenge to her position.

女主席面临她职位的最大挑战。

《柯林斯英汉双解大词典》

The greatest challenge for the Americans is understanding the mindset of Eastern Europeans.

对美国人来说，最大的挑战在于理解东欧人的思维方式。

《柯林斯英汉双解大词典》

That is the greatest challenge of all.

对于所有人来说，这是一次前所未有的巨大挑战。

youdao

Entrepreneur Emil Umetaliev points to what he says is the interim government's greatest challenge.

VOA: standard.2010.04.15

The greatest challenge for both of them is to walk hand in hand in coming years.

CNN: From Our Correspondent: A Gift From Korea

The greatest challenge for big-power diplomacy today is non-proliferation, keeping shut the door to the nuclear club.

NPR: U.S. Loses Its Edge in Nuclear Talks

For many candidates, getting a foot in the door is the greatest challenge in landing a job.

FORBES: Is The Career Fair Dead?