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Analysts say the biggest problem is high unemployment, which weakens demand and makes banks reluctant to lend.

分析者说，最大的问题是高失业率，这会导致借贷需求减少以及银行不愿意放贷。

youdao

Almost everyone who was interviewed for this special report said that the biggest problem at the moment is not a lack of demand but a lack of good work to sell.

几乎每一位接受本期特别报道采访的人都表示，目前最大的问题不是需求不足，而是缺乏可供销售的好作品。

youdao

She says the biggest problem was feeling very alone as a woman in science.

VOA: special.2009.05.13

What do you think is the biggest problem about living in LA?

你觉得住在洛杉矶最大的问题是什么？

大众交通枢纽 - SpeakingMax英语口语达人

And Widow Maker,in the end, caused the biggest problem for Pecos Bill.

VOA: special.2009.11.28

The biggest problem Google is likely going to encounter is a demoralized organizational culture.

FORBES: Is Google Crazy? Or Crazy Like a Fox?

Perhaps the biggest problem facing IT today is that its accounting practices are substantially immature.

FORBES: The Coming Crisis of IT Management

The biggest problem with that solution should be obvious: many of the complaints are hardware related.

FORBES: Why Amazon's Fire Solution Is Also A Problem