The SDCT2 with C-terminal deletion was almost entirely distributed at the basolateral membrane, nearly not expressed at the apical membrane, and seldom expressed in the cytoplasm.
端缺失的SDCT2蛋白主要位于基底侧膜上,顶膜几乎没有表达,细胞质中表达很少。
Cytochrome oxidase is the terminal component of the mitochondrial electron transport chain and is an integral protein complex of the inner mitochondrial membrane.
细胞色素氧化酶是线粒体电子传递链的最终构成部分,且是线粒体层的完整蛋白质复合体。
The above results suggested that the N-terminus of SDCT2 is required for its subcellular localization and the basolateral membrane localization signal of SDCT2 locates in the N-terminal sequence.
这表明SDCT2蛋白的N端序列对其亚细胞定位是必需的,人SDCT2蛋白的基底膜定位信号位于N端序列中。
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