Most of us like challenges, so take up a challenge like volunteering yourself for a new project.

我们大都喜欢挑战，因此接受挑战，比如主动参与新项目的筹备。

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When Hofmann made some passing comments about the desirability of a synthetic substitute for quinine, it was unsurprising that his star pupil was moved to take up the challenge.

当霍夫曼对奎宁的合成替代物的可取性发表完一些简短的评论后，他的得意门生接受挑战也就不足为奇了。

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If you take on a long-term challenge, show a deep commitment to the process and a refusal to give up in the face of adversity, your kids will pick that up instead.

如果你能树立一个长期的挑战目标，在过程当中坚持不懈，在逆境当中永不放弃，那么你的孩子们也将依样学之。

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And for me it's fun because I may not know the novel that you end up picking, and so it is a kind of challenge for me to take a novel that you've chosen and come to grips with it myself It may be one that I know.

我也觉得很好玩,因为我可能不知道你们最后选择的小说，所以对我来说,认真对待你们选的一本书很有挑战性,可能是一本我知道的书。

耶鲁公开课 - 1945年后的美国小说课程节选

The former Gills boss and midfielder decided to call it a day at Priestfield Stadium to take up a fresh challenge.

BBC: Hessenthaler won 77 of 228 games as manager at the Gills

Instead I have focused on humility, trust, perseverance, creativity and the simple desire to step up and take on a challenge and make the world a better place.

FORBES: The Hobbit: An Unexpected Leadership Journey

To take up this challenge, UNESCO has a decisive role to play.

UNESCO: THEMES