I must take issue with you on that point.

我必须就那一点向你提出异议。

《牛津词典》

In line with the promise of this age, I want to exhort each of the graduates here to take on an issue – a complex problem, a deep inequity, and become a specialist on it.

同 这个时代的期望一样，我也要向今天各位毕业的同学提出一个忠告：你们要选择一个问题，一个复杂的问题，一个有关于人类深刻的不平等的问题，然后你 们要变成这个问题的专家。

youdao

That's why I can't take sides on this issue and I'm not going to.

这就是为什么在这个问题上我没法选边站的原因，以后也不会。

youdao

When the Food and Drug Administration does issue new limits on salt, the changes on the menu and on grocery food labels will take time to implement.

VOA: standard.2010.04.22

What this is, is you take a group of studies on an issue, you pool them all together, and then you weight studies differently depending on factors like how large they were, how good their methods were, and then you come out with overall estimates about the impact of something, in this case the Mediterranean Diet, on health outcomes.

所谓荟萃分析就是将某一问题的一组研究,汇总起来,并根据某些因素,赋予这些研究不同的权重,如基于研究的大小,研究方法的好坏等,然后得出关于某事物的影响的总体评估,在地中海式饮食中就是指健康结果

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

Lois Fischbeck of Maryland came to urge the court to ban capital punishment, even though the justices are not scheduled to take on a particular case this term that would deal with the issue directly.

VOA: standard.2009.10.05

The speaker said she would have to take counsel on the issue and rule on it on Tuesday.

BBC: NEWS | UK | Northern Ireland | NI politicians return to Stormont

So, i am sorry to say that I must take issue with your perspective on this matter.

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Naturally, companies that use water as a key ingredient are going to be the first in line to take on the issue.

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