A life of tedious isolation - or an ability to take challenge in your stride?

是沉闷隔绝的生活，还是泰然面对挑战的能力？

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I hope you'll take the challenge and find incredible joy in the process.

我希望你也接受挑战，然后在这一过程中发现极大的乐趣。

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When Hofmann made some passing comments about the desirability of a synthetic substitute for quinine, it was unsurprising that his star pupil was moved to take up the challenge.

当霍夫曼对奎宁的合成替代物的可取性发表完一些简短的评论后，他的得意门生接受挑战也就不足为奇了。

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"Every fish we take out there is one less fish to challenge the electric barrier further upstream yet."

VOA: standard.2010.07.19

And for me it's fun because I may not know the novel that you end up picking, and so it is a kind of challenge for me to take a novel that you've chosen and come to grips with it myself It may be one that I know.

我也觉得很好玩,因为我可能不知道你们最后选择的小说，所以对我来说,认真对待你们选的一本书很有挑战性,可能是一本我知道的书。

耶鲁公开课 - 1945年后的美国小说课程节选

That is our basic challenge now,". Geithner says it will take some time to bring down unemployment levels, which in October reached a 26-year high in the United States.

VOA: standard.2009.11.12

"If you're going to take on the challenge, take on the challenge, " he said.

WSJ: Allyson Felix's Olympic Hedge

But my goal is to challenge more schools and more communities to take part in this, particularly middle and high school students, because right now those 635 students are at the elementary school level, and we need to take this challenge up to kids in middle schools and high schools.

WHITEHOUSE: The First Lady Urges Healthy Diet and Exercise

But Ms Li does not believe the search giant will take the challenge lying down.

BBC: Searching for the next big thing