Results OSR(500.0,250.0 mg·kg-1,iv) could significantly increase the tail-flick latency,and the analgesic effect could last more than 90 min and the maximum rate of pain threshold could be up to 59.82%.
结果 OSR(500.0,250.0 mg.kg-1,iv)可明显延长小鼠温浴热甩尾潜伏期(P<0.05,P<0.01),药效可持续60 min以上,最大痛阈提高率可达59.82%。
参考来源 - 氧化槐定碱镇痛作用及其对小鼠中枢GABA·2,447,543篇论文数据,部分数据来源于NoteExpress
Methods The rats' pain threshold was measured by tail-flick latency after oral administration of anti-pain powder.
方法口服抗痛粉,用辐射热甩尾法测定大鼠痛阈。
The changes of pain-excited neurons, pain-inhibited neurons, and tail-flick latency were taken as observation indexes of pain threshold.
以痛兴奋神经元、痛抑制神经元和甩尾潜伏期的变化作为痛阈的观察指标。
The analgesic effects of CPI were observed by acetic acid inducing writhing model and light radiant heat inducing tail-flick latency in mice.
采用光辐射热甩尾法和醋酸扭体法,观察CPI的镇痛作用。
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