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For instance, when you do combustion studies, flames on Earth burn in a teardrop fashion because the air comes in from underneath it and feeds the flame, but we can't do that here since the air doesn't know where up is, there's no convection.
WHITEHOUSE: President Obama's call to the International Space Station
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"Once it gets dark out there and the snow keeps falling and they have no air support, I don't know how effective they would be in that situation, " she told reporters.
CNN: February 9, 2013 -- Updated 1735 GMT (0135 HKT)
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For that reason, the Federal Aviation Administration issued an advisory in 2003 to airlines saying that passengers should be removed from planes within 30 minutes if there's no air circulation, but compliance isn't mandatory.
WSJ: Where Germs Lurk on Planes