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Objective to determine the expression level of CD69 on CD4 + and CD8 + t cells in peripheral blood from children with rheumatoid arthritis (ra), and investigate their role in the pathogenesis of ra.
目的分析小儿类风湿关节炎(RA)患者的外周血cd4 +、CD 8 + T细胞CD 69表达水平，探讨其在小儿关节炎症发生过程中的免疫病理作用。
Conclusion: GRP peptide is epitopes of t cells in some RA patients.
结论：GRP肽是部分类风关患者关节内t细胞的T细胞表位。
Histopathologic features of RA encompass infiltration by macrophages and T cells synovial lining hyperplasia, neoangiogenesis, pannus formation and destruction of cartilage and bone.
其主要病理特点是滑膜细胞增生、衬里层增厚、多种炎性细胞浸润、血管翳形成，以及软骨和骨组织的破坏。
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