Targeted intrapulmonary delivery of drugs may reduce systemic toxicity and improve treatment efficacy.
肺内定向给药可减少药物的系统毒性，提高疗效。
Results 2 of 16 cases (12.5%) relapsed. 5 cases complained of local toxicity with no systemic toxicity happened.
结果16例患者中有2例复发（12.5％），5例患者出现局部毒性反应，无全身毒性反应发生。
Conclusion: CHIP provides high concentration of DDP in the peritoneal cavity, inducing higher local tumoricidal effect, lower nephric and systemic toxicity.
结论：CHIP腹腔ddp浓度高，血浆峰值较低，以及高温作用，有利于化疗药物在局部对肿瘤细胞发挥作用，减少肾毒性和全身副作用。
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