Clinical interest has hitherto largely focused on pathology in the retina as a manifestation of known systemic disease, such as diabetes or hypertension.

迄今为止，临床兴趣的焦点主要集中于视网膜作为已知的系统性疾病的表现的病理学上，如糖尿病或高血压。

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Systemic Lupus Erythe-matosus ( SLE) is an autoimmune disease of unknown cause. SLE model mice are of many immune and pathology abnormality similarly with human.

系统性红斑狼疮（SLE）是一种原因未明的自身免疫性疾病，其许多免疫学异常及组织病理变化均可在SLE小鼠模型中见到。

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