Background-PRKAG2 mutations cause glycogen-storage cardiomyopathy, ventricular preexcitation, and conduction system degeneration.

背景- PRKAG2突变引起糖原贮积型心肌病，心室预激和传导系统退化。

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Damage to the central nervous system (CNS) is always followed by an irreversible axon degeneration of injured neurons.

成年哺乳动物中枢神经系统(CNS)损伤，常导致神经元死亡及轴突不可逆的退化。

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Objective To localize the functional involvement of the central nervous system (CNS) in patients with subacute combined degeneration (SCD).

目的探讨亚急性联合变性（SCD）患者中枢神经系统（CNS）功能受累的部位。

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Huntington's disease is an hereditary neurological disorder of the central nervous system that causes progressive degeneration of cells in the brain, slowly impairing a person's ability to walk, think, talk and reason.

BBC: Rookwood Hospital, Cardiff

They showed how high cholesterol levels could affect the immune system and lead to macular degeneration.

BBC: Macular degeneration: Cholesterol drugs 'may save sight'

The goal is to prevent the degeneration of the nervous system and brain that is caused by the disease.

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