First Biggar's swiftpass found James Hook drifting just outside his marker and the centre raced through a gap to send Shane Williams racing over for a try on his 100th Ospreys appearance.
Malouda rounded off a fine passing move with a sweet back-post finish to make it 2-0 and Lampard practically walked the ball into the net when he met substitute Nicolas Anelka's pass from another swift breakaway.