In reviewing the charts of children under 18 seen in two Boston EDs from 2001 to 2006, the researchers identified 1,255 children who made visits for food-related allergic reactions. Of these, more than half had anaphylaxis, the most severe allergic reaction involving at least two organ systems or low blood pressure (as defined by the National Institute of Allergy and Infectious Disease and the Food Allergy and Anaphylaxis Network in 2006). Common symptoms included trouble breathing, skin rashes, swelling and gastrointestinal problems.

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