The research was aiming at the preparation of compound tramadol 12h sustained-release pellets and validation in vivo,consisting of preparation methods for pellets, the sustained-release system of coated pellets, stability, pharmacokinetics.
本文进行了复方盐酸曲马多缓释微丸的处方前、制剂学、稳定性及药动学研究。
参考来源 - 复方盐酸曲马多缓释微丸的研制Using L9(34) orthogonal experiment to select the recipe or the floating pellet’s recipients and study the release action of the sustained-release pellets in vitro by rotational method. Based on the characteristic of the cumulate-release curve,filtrate the best recipe.
采用L9(34)正交实验,筛选辅料的处方,并用转篮法研究缓释微丸的体外释放行为,根据累积释放曲线的特性,筛选出最佳处方。
参考来源 - 雷公藤缓释微丸的研制·2,447,543篇论文数据，部分数据来源于NoteExpress
OBJECTIVE To prepare ribavirin sustained-release pellets by centrifugal granulation technology.
目的研究离心造粒粉末层积法制备利巴韦林缓释微丸。
Objective To prepare aciclovir sustained-release pellets and investigate the drug release mechanism in vitro.
目的制备阿昔洛韦缓释微丸，并对其体外释药情况进行研究。
Conclusion This method is simple, rapid and accurate, which is suitable for the quality control of sinomenine hydrochloride sustained-release pellets.
结论该方法简便、准确、快速，可用于盐酸青藤碱缓释微丸的含量测定及质量控制。
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