Bacterial surface display, in which heterologous peptides and proteins are fused withthe bacterial surface proteins and expressed on the surface of recombinant bacteria hasprovided a new method to construct live recombinant vaccines.
细菌表面呈现是将外源蛋白或多肽与细菌表面蛋白融合或嵌合并活性表达于细菌表面,细菌表面呈现技术的出现为构建基因工程活菌疫苗提供了一条崭新的途径。
参考来源 - 表达外源基因的鸡源大肠杆菌1型菌毛载体的初步构建Recently, the baculovirus have been successfully developed as expression vector system, recombinant bio-insecticide, gene transfer vector and surface display vector, providing huge benefits to nature science development.
近年来,发展而成的杆状病毒表达系统、重组杆状病毒杀虫剂、杆状病毒基因治疗载体和杆状病毒表面展示系统为科学研究作出了巨大的贡献。
参考来源 - BmNPV三个杆状病毒核心基因分析·2,447,543篇论文数据,部分数据来源于NoteExpress
M13 bacteriophage has been extensively applied in phage surface display technique.
M 13噬菌体已被广泛地应用于噬菌体展示技术。
Moreover, L-form bacteria can also be applied as active proteins in cytoplasmic membrane surface display.
此外,L -型细菌还能将具有功能活性的蛋白展示在胞浆膜表面。
Conclusion Phage surface display technology is a useful method to produce human monoclonal antibody against CEA.
结论噬菌体抗体库技术是研制人源性单抗的有效途径。
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