宋磊等采用溶液上药法（流化床底喷装置）制备苦参碱微丸，并进行微丸质量评价及粉体学性质研究；用苏丽丝（Surelease）作为包衣材料、微型流化床进行包衣，对微丸体外释放进行评价并考察热处理对微丸释放的影响。
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Methods:Immediate release pellets were manufactured by extrusion/spheronization technology. The operation of bottom-spraying in the fluid-bed equipment was conducted to enteric-coating using Eudragit L-30D-55 and sustained-release coating using Surelease.
方法:采用挤出滚圆法制备速释丸,流化床底喷包衣制备肠溶和缓释微丸。
参考来源 - 盐酸青藤碱缓释组合微丸系统的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
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