In order to produce crystalline material it is preferred to use a salt of 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-3-hydroxy-1-propanyl L-valinate. Preferred crystalline salts are the acetate and the hydrochloride salt. It is preferred to initiate crystallization of the salt by dissolving the hydrochloride or acetate salt in water and adding an organic solvent miscible with water such as methanol, ethanol, isopropanol, tetrahydrofuran or acetonitrile. Alternatively, the hydrochloride salt can be crystallized from an anhydrous lower alkanol solution, such as methanol, ethanol, by the addition of other organic solvents such as ethyl acetate, isopropanol, tetrahydrofuran or toluene.
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The solvent system includes a lower alkanol such as methanol or ethanol and cyclohexene.
该溶液体系包括低级烷醇如甲醇,乙醇和环己醇。
They used a special polymer, a different sort of charged particles known as counterions and solvents such as methanol.
他们采用了一种特殊的聚合物,一种被称为反离子的不同类型的带电粒子和溶剂(如甲醇)。
Ever since, fuel cells burning hydrogen or other fuels such as methanol have been touted as clean, quiet and green power sources.
自此自后,使用氢氧或其他像甲醇等燃料的燃料电池就被冠以清洁,安静绿色能源的名号而被大力追捧。
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