It can manage the air consumption for substantial saving by detecting pressure, flow and accurately calculate the instantaneous power.

可以检测压力、流量并准确计算出瞬时功率，从而管理压缩空气能耗，实现大幅节能。

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That has cut capital on hand by hundreds of millions of dollars, a substantial percentage of the bank's capital, saving millions a year in funding costs.

FORBES: From nuclear bombs to net assets

Their statement coincided with the 10th anniversary of an open letter written by the late Nobel Laureate Milton Friedman, explaining that the estate tax ties up capital, punishes saving and investing, fails to raise substantial revenue, and increases economic inequality.

FORBES: To Reduce The Deficit, Kill The Estate Tax

And substantial risks often have to be accepted in pursuit of life saving medical benefit.

BBC: What we can learn from fatal mistakes in surgery