There is a substantial difference between the dialectics without identity and "Negative dialectics".

没有同一性的辩证法与否定的辩证法是存在基本差别的。

youdao

These suggest there can be a substantial difference between how old you are and how old your blood vessels are.

这些工具可以告诉你年龄和血管年龄之间的实质性差异。

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We have passed a range of standards which will make a substantial difference in the safety and quality of the food people eat.

我们已通过一系列标准，它们将对民众所吃食品的安全和质量产生巨大影响。

youdao

Still, there was a substantial difference between the life spans of junior and senior civil servants.

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Which makes a substantial difference in places like California and New York (and even more in NYC).

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"If the house is the Kips Bay show house, I think it makes a substantial difference, " he said.

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