Paul Gambaccini and a documentary strand will take the Saturday night slot vacated by Russell Brand.

BBC: O'Grady and Carr join BBC Radio 2

"First class" pertains to body parts of saints--a fingernail of the Apostle Paul, say, or a strand of the Virgin Mary's hair.

FORBES: Magazine Article

The terms sense and antisense were coined by Paul Zamecnik to show the complementary, double-strand nature of DNA. One strand consisted of alternating patterns of the four nucleotides that make up DNA adenine, cytosine, guanine and thymine and it could be read in order.

FORBES: Antisense and Sensibility