The amides’catalytic activity and stereoselectivity is lower than that have been reported in this area. We argue that the structure of carboxyl group have negative effect on the enantioselectivity.
酰胺类催化剂的催化活性和对映选择性比该领域中已报道的催化剂的要差,我们认为羧基结构不利于对映选择性的提高。
参考来源 - LAnd enzymes would also show up stereoselectivity to entiomers, altering or even deteriorating the accretion rate of one of them.
对于对映体来说,酶还表现出立体选择性的差异,从而可能使其中占主药效的一个对映体的代谢速度改变甚至逆转。
参考来源 - 普萘洛尔对映体在经不同诱导剂诱导的人肝细胞中的代谢特征·2,447,543篇论文数据，部分数据来源于NoteExpress
以上来源于: WordNet
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