International Hepatology: Besides the important role of hepatic stellate cell in liver fibrosis development, are there any other important mechanisms involving liver fibrosis development?
国际肝病:除了肝星状细胞在肝纤维化发生中的重要作用,还有哪些机制参与了肝纤维化的发生?
Objective To observe the effects of recombinant augmenter of liver regeneration (ALR) on the proliferation of hepatic stellate cell line IG12 and ECM synthesis.
目的观察重组大鼠肝再生增强因子(alr)对肝星状细胞株ig12增殖及细胞外基质合成的影响,探讨其抗肝纤维化作用的可能机制。
The activation of hepatic stellate cell phenotype change and secretion of extracellular matrix of liver fibrosis is the central link.
肝星状细胞的激活、表型改变并分泌大量的细胞外基质是肝纤维化发生的中心环节。
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