One response to such inertia has been the spread of target-date funds, which rebalance automatically as the participant nears retirement age, and target-risk funds, which are managed and rebalanced according to a saver's risk tolerance, as opposed to his age.
Prof Swanton said the findings underlined the importance of early diagnosis of cancer before it had spread, and the need to target the common mutations in the 'trunk' of the cancer.
And both target men with prostate cancer that has spread elsewhere in the body or returned despite treatment designed to hamper testosterone production.