转录的RNA需经剪接体(Spliceosome)成熟之后再翻译成蛋白质,执行生物学功能。剪接体(Spliceosome)是一个巨大而又复杂的动态分子机器,清华大学施一公课题组创新性地利用酵母细胞内源性蛋白提取获得了性质良好的样品,并利用前沿...
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spliceosome cycle 剪接体周期 ; 剪接体循环
catalytic step I spliceosome 第一步催化反应后
pre-spliceosome 剪接体
spliceosome complex 剪接体复合物
The Spliceosome Dance 剪切子的模拟动画
spliceosome-associated proteins 剪接体相关蛋白
Assembly and transitions of spliceosome 剪接体的组装和动态变化
Any mutation in the porypyrimidine (py) tract and the branch point consensus sequence of introns that affected splicing did so by interfering with efficient spliceosome assembly and splicing of pre - mRNAs.
内含子的嘧啶富集区the polypyrimidine(py)tract和支点一致序列(the branch point consensus sequence)中的任何突变都将通过干扰剪接体组装效率和mRNA前体(premRNA)的剪接直接影响剪接过程。
参考来源 - 喉癌p53基因突变和STK15基因过表达与中心体异常相关性研究·2,447,543篇论文数据,部分数据来源于NoteExpress
以上来源于: WordNet
Objective: NIPP1 is a ubiquitous nuclear protein of the protein in the nucleus, spliceosome assembly it must be yes.
目的:NIPP 1核蛋白是一种普遍存在于细胞核中的蛋白,它在剪接体的装配中必须是的。
Spliceosome assembly occurs co-transcriptionally, raising the possibility that DNA structure may directly influence alternative splicing.
剪接体组装与转录同步进行,提示DNA结构可能直接影响可变剪接。
RNA splicing is carried out by the spliceosome, which is a large, dynamic complex composed of more than a hundred proteins and several small nuclear RNAs.
RNA剪接是由一个上百个蛋白质和数条小核r NA组成的复杂的动态复合体完成的。
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