Both the integral membrane and soluble splice variants are biologically active (1).

完整的细胞膜和可溶性的剪接形式都具有生物活性(1)。

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However, presence and possible roles of FN splice variants and fragments in human IVD have not been determined.

但是，FN连接变异体和人类IVD片段的存在和可能作用还未得到证实。

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FN splice variants play important roles in regulating cell-matrix and matrix-matrix interactions in skeletogenesis and skeletal function in limbs and other sites.

FN剪切变异体在调节细胞基质，基质与基质间的相互作用，骨骼发育和四肢骨骼功能及其他方面起到很重要的作用。

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