SIP, which play important roles in diverse biological processes such as cell proliferation, migration and survival, is produced by metabolism of the membrane phospholipid sphingomyelin.
鞘氨醇-1-磷酸盐(S1P)是质膜鞘磷脂的代谢产物,也是重要的生物活性物质,可调节细胞的增殖、迁移、分化、死亡等。
参考来源 - 肝细胞生长因子诱导细胞增殖和迁移的机制研究Lipid rafts,as defined by Simoms and Ikonen are unique membrane micro-domains,which contain large amount of cholesterol and sphingomyelin.
脂筏是细胞膜上的特殊微区,其中含有大量的胆固醇和鞘磷脂,因为这两种脂类的稳定性较强,可以使脂筏微区与其它磷脂双层分相,并为许多膜蛋白和病原体提供进出细胞和下传信号的平台。
参考来源 - 脂筏在TRAIL引起的细胞凋亡早期事件中的作用研究·2,447,543篇论文数据,部分数据来源于NoteExpress
以上来源于: WordNet
N any of a group of phospholipids, derived from sphingosine, that occur in biological membranes, being especially abundant in the brain 鞘磷脂 [biochem]
CONCLUSION Sphingomyelin can be obtained from erythrocyte membrane by this method.
结论用此法可将红细胞膜中的鞘磷脂降解成神经酰胺。
OBJECTIVE To extract the sphingomyelin from erythrocyte membrane and hydrolyze it to ceramide.
目的从红细胞膜中提取鞘磷脂并降解成神经酰胺。
High sphingomyelin phosphodiesterase-producing Actinomucor elegans mutant(AE255-6) was obtained by radiation of CO2 laser.
用CO2激光辐射筛选培育出高产鞘磷脂酶的工程菌——雅致放射毛霉变异株AE255-6。
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