What's the matter? Is there something wrong?

怎么了？出了什么事儿吗？

《牛津词典》

There's something wrong with the TV.

电视出毛病了。

《牛津词典》

I have something wrong with my foot.

我的脚有点儿不对劲。

《牛津词典》

And those without training may not do anything for fear that they will do something wrong.

VOA: special.2009.06.09

We don't give ourselves the permission to be human, because we think there is something wrong with us if we experience these emotions.

我们不准许自己为人，因为我们觉得是自己有毛病,如果我们有这样的情绪。

哈佛公开课 - 幸福课课程节选

What I mean is when you wish to express that you are sorry if you've done something wrong

在这里我是指，你想要表达的是，如果你确实有过失，你感到很抱歉，

I'm sorry 课堂 - SpeakingMax英语口语达人

Just play by the rules, so that if something wrong happens, here's who's responsible.

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But cheating is doing something wrong, and there are no two ways about it.

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He felt something wrong in his groin, and it was wise to come off.

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