It is almost certainly doing something significant in adults as well as in fetuses.

几乎可以肯定的是，它在成人和胎儿身上都起着重要的作用。

youdao

We dream of doing something big and splashy, something significant.

我们的梦想做了一些大国和泥泞，但意义重大。

youdao

We dreamed of doing something big and splashy, something significant.

我们都梦想过做一番大事业，做有意义的事情。

youdao

"When you put that all together it suggest that we are going to need something like 50 percent more, perhaps 100 percent more, food from our existing land and that is a very significant challenge and we believe we need to be thinking seriously about that right away,"

VOA: standard.2009.10.21

And the top answer that was 82% was the Internet, something like 60% said they thought the availablity of guns was a significant factor in the Columbine's shooting.

高达82%的人认为是因为网络，约有60%的人认为,枪支的使用是一个重要因素,造成了这起枪杀案。

麻省理工公开课 - 媒体、教育、市场课程节选

Nevertheless, to secure the distinction in actual practice, to say, "Okay. This is the meaning and now this is how I'm going to make it significant" -well, it seems unlikely indeed that this is something anyone could ever accomplish.

然而，若在实际操作中,你试着去体现这个区别，你会说，好的，这是意思,现在我来将它变成意义“,可是，实际上似乎谁都,无法完成这个任务。

耶鲁公开课 - 文学理论导论课程节选

We believe that this is an important moment, a rare opportunity to do something significant.

WHITEHOUSE: Press Briefing

And that really is the only way here if we want to do something significant.

WHITEHOUSE: Press Briefing

It think there's something significant that's coming to a point here in the city.

NPR: SUPER BOWL WATCH: Beyonce, Avocados, Practice