Objective To investigate the features of somatic mutations and polymorphisms of mitochondrial D loop regions in breast cancer.
目的探讨乳腺癌的线粒体基因D环区的体细胞性突变和多态性变异特征。
Tumor biopsies were evaluated for the presence of somatic mutations in exons 18-21 of EGFR and exon 2 of RAS by bi-directional sequencing.
对肿瘤组织进行或组织检查以检测EGFR的18—21外显子的突变并应用双向测定法检测RAS的2外显子的突变。
To arrive at these conclusions, researchers analyzed about 500,000 cancer mutation records from the Catalog of Somatic Mutations in cancer database and then divided the data into 45 tissue types.
为了得到这些结论，研究者在癌症数据库细胞突变分类中分析了大约50万条癌突变记录，并把这些数据分为45种组织类型。
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